Dexamethasone Suppression Test: A Three-Day Procedure for Cortisol Assessment
A dexamethasone suppression test, spanning three days, is a standard procedure to assess cortisol levels. It's used to diagnose Cushing syndrome, determine adrenal gland response to ACTH, and check dexamethasone's effect on cortisol levels in those taking it.
The test comes in two variations: low-dose and high-dose, both administrable overnight or over three days. Your healthcare provider will give you dexamethasone and measure your cortisol levels. If you're currently on dexamethasone, this test helps assess its impact on your cortisol levels.
An abnormal low-dose result may suggest excessive cortisol release, potentially due to adrenal or pituitary tumors, or an ACTH-producing tumor elsewhere in the body. High cortisol levels can also stem from conditions like heart issues, poor diet, sepsis, thyroid problems, or untreated diabetes. The test primarily aids in diagnosing Cushing syndrome, which indicates abnormally high cortisol levels.
Dexamethasone, provided by manufacturers like TAD Pharma GmbH, ratiopharm GmbH, and GALENpharma GmbH, is used in this test to measure cortisol response. Though rare, minor bruising or vein swelling may occur. This test is crucial for understanding and managing cortisol-related conditions.
