Reason for advising oral contraceptives prior to In Vitro Fertilization procedures
In the realm of assisted reproductive technology, Birth Control Pills (BCPs) have found a surprising yet beneficial role in increasing the effectiveness of In Vitro Fertilization (IVF) treatment.
BCPs, oral contraceptives that contain synthetic versions of the naturally occurring hormones estrogen and progesterone, can help improve the efficiency of IVF treatment by scheduling the optimal timing. By regulating and suppressing the natural menstrual cycle, BCPs make it easier to manage and schedule the timeline of IVF treatment [1].
One of the key advantages of using BCPs in an IVF cycle is their ability to synchronize the development of follicles, making the IVF cycle more controlled and predictable. This synchronization can help prevent the premature development of follicles before stimulation starts, potentially improving the ovarian response to fertility medications [1][3].
It's important to note that the effect of taking BCPs before IVF on success rates is more about cycle control rather than directly increasing pregnancy chances. They help optimize the environment for ovarian stimulation and egg retrieval by starting the stimulation phase at an ideal time. However, pregnancy success depends mainly on other factors such as ovarian reserve, embryo quality, and uterine receptivity [1][3].
Typically, the recommended duration for taking BCPs before starting an IVF cycle ranges from about 1 to 2 weeks. These pills are often used at the start of the menstrual cycle prior to ovarian stimulation [1].
While BCPs can be a valuable tool in the IVF process, it's crucial to remember that they may not be suitable for everyone. Certain individuals, such as those older than 35 who smoke, individuals with a history of breast cancer, heart attack or stroke, blood clots, high blood pressure, migraine with aura, and those with other specific medical conditions, should avoid BCPs [2].
Before embarking on an IVF journey with BCPs, it's essential to consult a doctor to discuss options, potential risks, and individual suitability. The doctor may also suggest using BCPs to help control a person's menstrual cycle and ovulation period, making it easier to manage and schedule the timeline of IVF treatment [4].
Common brand-name BCPs include Azurette, Kariva, Enpresse, Seasonique, and Ocella. However, individuals taking BCPs may experience negative side effects that can range from mild effects to serious effects [5].
In summary, BCPs can be a valuable addition to the IVF process, helping to regulate and synchronize the menstrual cycle, schedule treatment, and improve the timing of ovarian stimulation. However, their use is just one component of the overall treatment protocol and success ultimately depends on multiple clinical factors [1][3].
References:
[1] American Society for Reproductive Medicine. (2019). Controversies in Ovarian Stimulation for IVF. Retrieved from https://www.asrm.org/globalassets/asrm/asrm-us/resources-and-publications/practice-guidelines-and-clinical-consensus-statements/clinical-consensus-statements/controversies-in-ovarian-stimulation-for-ivf.aspx
[2] Mayo Clinic. (2021). Birth control pills: Who shouldn't take them. Retrieved from https://www.mayoclinic.org/tests-procedures/birth-control-pills/in-depth/birth-control-pills/art-20044208
[3] Human Fertilisation and Embryology Authority. (2020). Ovarian stimulation. Retrieved from https://www.hfea.gov.uk/treatments/ivf-and-injections/ovarian-stimulation/
[4] American Society for Reproductive Medicine. (2019). Controversies in Ovarian Stimulation for IVF. Retrieved from https://www.asrm.org/globalassets/asrm/asrm-us/resources-and-publications/practice-guidelines-and-clinical-consensus-statements/clinical-consensus-statements/controversies-in-ovarian-stimulation-for-ivf.aspx
[5] NHS. (2021). Side effects of the combined pill. Retrieved from https://www.nhs.uk/conditions/contraception/combined-pill/side-effects/
Women's health and health-and-wellness can benefit from the use of birth control pills (BCPs) in the field of women's health, as they help regulate the menstrual cycle and improve the timing of ovarian stimulation during In Vitro Fertilization (IVF) treatment. Science has shown that BCPs can synchronize the development of follicles, making IVF cycles more controlled and predictable, potentially improving ovarian response. However, the use of BCPs is only one component of the overall treatment protocol, and pregnancy success depends on multiple clinical factors such as ovarian reserve, embryo quality, and uterine receptivity. It is essential for individuals to consult a healthcare provider before embarking on an IVF journey with BCPs to discuss the potential risks, individual suitability, and alternative options.
